{"id":1570,"date":"2021-10-10T13:13:10","date_gmt":"2021-10-10T13:13:10","guid":{"rendered":"https:\/\/blog.skincancer.org\/?p=546"},"modified":"2025-01-17T20:35:26","modified_gmt":"2025-01-17T20:35:26","slug":"dangerous-melanoma-matter-timing","status":"publish","type":"post","link":"https:\/\/www.skincancer.org\/blog\/dangerous-melanoma-matter-timing\/","title":{"rendered":"How Dangerous is Melanoma? It\u2019s All a Matter of Timing","gt_translate_keys":[{"key":"rendered","format":"text"}]},"content":{"rendered":"<p><a href=\"https:\/\/www.skincancer.org\/skin-cancer-information\/\">Skin cancer<\/a> holds the unfortunate distinction of being the world\u2019s most common cancer. Though its prevalence around the globe is disturbing, there is some good news: When <a href=\"https:\/\/www.skincancer.org\/early-detection\/\">caught early<\/a>, skin cancers are highly curable.<\/p>\n<p>You might already know that catching a cancer early means a more favorable prognosis. But it can be difficult to comprehend just how big a difference early detection makes with melanoma, the most dangerous form of skin cancer. <a href=\"https:\/\/www.skincancer.org\/skin-cancer-information\/melanoma\/\">Melanoma<\/a> should never be underestimated, but treating a tumor early rather than after it is allowed to progress could be lifesaving.<\/p>\n<p>Leland Fay, 46, understands better than most the seriousness of this distinction. When the Monument, Colorado native was diagnosed with melanoma in 2012, he was given a bleak prognosis due to the advanced stage of the tumor \u2014 it had already reached <a href=\"http:\/\/www.skincancer.org\/skin-cancer-information\/melanoma\/the-stages-of-melanoma\">stage IV<\/a>.<\/p>\n<p>Leland hadn\u2019t thought much of the little black mole on his head a few months earlier, when a dermatologist froze it off during a routine exam. But the mole resurfaced, bigger than it had been originally. After a biopsy and imaging tests, doctors told Leland it was melanoma, and that it had already spread. He could have as few as six weeks to live.<\/p>\n<p>Luckily, with the help of several surgeries, <a href=\"https:\/\/www.skincancer.org\/skin-cancer-information\/melanoma\/melanoma-treatments\/\">immunotherapy<\/a>, radiation and the \u201cfaith and support of family and friends,\u201d Leland overcame the odds. He still goes in for treatments, but five years after his diagnosis, he is leading an active, full life. He recognizes, however, how different his journey could have been if the melanoma was caught earlier: \u201cBetter to have a little inconvenience with a biopsy than let melanoma advance.\u201d<\/p>\n<p>To fully comprehend the significance of timing, it can be helpful to understand exactly what happens to a melanoma when it advances to a later stage, and what it means when a melanoma spreads beyond the original tumor site.<\/p>\n<h3><strong>Scratching the Surface<\/strong><\/h3>\n<p>A <a href=\"https:\/\/www.skincancer.org\/skin-cancer-information\/melanoma\/the-stages-of-melanoma\/#stages\">melanoma in its earliest stages<\/a> is localized. This means that the tumor\u2019s malignant cells have not multiplied to the point that they extend beyond the skin. The very earliest melanomas (stage 0) do not even extend past the top layer of the skin, the epidermis. These tumors are called <em>in situ<\/em>, a Latin phrase that means \u201cin (original) position,\u201d and they are considered noninvasive. If a tumor penetrates deeper, into the dermis, it is considered <em>invasive<\/em> (stages I and II). On average, the estimated five-year survival rate for melanomas detected while still localized is very high: about 99 percent in the U.S.<\/p>\n<h3><strong>Digging Deeper<\/strong><\/h3>\n<p>The chances of curing a melanoma drop sharply once it spreads, or metastasizes, beyond the original tumor site. Normally, the first place a melanoma tumor metastasizes to is the lymph nodes, by literally draining melanoma cells into the lymphatic fluid, which carries the melanoma cells through the lymphatic channels to the nearest lymph node basin. Lymphatic fluid is an important part of the immune system that bathes the tissues, and is responsible for carrying foreign invaders like bacteria to the lymph nodes, where these invaders are destroyed by the lymphocytes, the white blood cells.\u00a0 Unfortunately, when melanoma cells are carried to the lymph nodes, they can potentially be carried beyond the nodes to distant organs. Once a melanoma has metastasized beyond the original tumor site, either to the skin en route to the lymph nodes (\u201cin transit\u201d metastases) or to the lymph nodes themselves, it is considered a stage III melanoma. The five-year survival rate then drops to <a href=\"https:\/\/www.skincancer.org\/skin-cancer-information\/skin-cancer-facts\/#melanoma\">around 74 percent<\/a> because of the high risk that the cancer can spread from the nodes throughout the body.<\/p>\n<p>Once a tumor has spread to distant body sites such as organs, it is considered a stage IV melanoma, with an estimated five-year survival rate of only <a href=\"https:\/\/www.skincancer.org\/skin-cancer-information\/skin-cancer-facts\/#melanoma\">35 percent<\/a> in the U.S. These survival figures are improving every year because of <a href=\"https:\/\/www.skincancer.org\/treatment-resources\/treatment-glossary\/\">new treatments<\/a> but they are no substitute for early detection.<\/p>\n<h3><strong>Stop Tumors in Their Tracks<\/strong><\/h3>\n<p>Every melanoma has the potential to become deadly, but the difference between an <em>in situ <\/em>melanoma and one that has begun to metastasize cannot be overstated. There is a drastic change in the survival rate for the various stages of tumors, highlighting the importance of detecting and treating melanomas before they have a chance to progress. It\u2019s impossible to predict exactly how fast a melanoma will move from stage to stage, so you should be taking action as soon as possible.<\/p>\n<p>To be sure you\u2019re spotting any potential skin cancers early, The Skin Cancer Foundation recommends <a href=\"https:\/\/blog.skincancer.org\/2017\/10\/09\/how-to-perform-a-self-exam\/\">monthly skin checks<\/a>, and scheduling an <a href=\"https:\/\/www.skincancer.org\/early-detection\/annual-exams\/\">annual total body skin exam<\/a> with a dermatologist. These skin exams can help you take note of any new or changing lesions that have the potential to be cancerous, and have them biopsied and taken care of before they can escalate.<\/p>\n<p>\u201cTrust your instincts and don\u2019t take no for an answer,\u201d Leland says. \u201cInsist that a doctor biopsy anything you believe is suspicious.\u201d<\/p>\n<p>&nbsp;<\/p>\n","protected":false,"gt_translate_keys":[{"key":"rendered","format":"html"}]},"excerpt":{"rendered":"<p>You might already know that catching a cancer early means a more favorable prognosis. But it can be difficult to comprehend just how big a difference early detection makes with melanoma, the most dangerous form of skin cancer. Melanoma should never be underestimated, but treating a tumor early rather than after it is allowed to progress could be lifesaving.<\/p>\n","protected":false,"gt_translate_keys":[{"key":"rendered","format":"html"}]},"author":3,"featured_media":1761,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[10],"tags":[9,5525,5526,23],"class_list":["post-1570","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-skin-cancer-information","tag-melanoma","tag-melanoma-danger","tag-melanoma-fatality","tag-treatment"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v25.3 (Yoast SEO v25.3) - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>How Dangerous is Melanoma? 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