{"id":1576,"date":"2023-10-30T12:58:41","date_gmt":"2023-10-30T12:58:41","guid":{"rendered":"https:\/\/blog.skincancer.org\/?p=594"},"modified":"2024-02-01T18:50:34","modified_gmt":"2024-02-01T18:50:34","slug":"defining-skin-cancer","status":"publish","type":"post","link":"https:\/\/www.skincancer.org\/blog\/defining-skin-cancer\/","title":{"rendered":"Defining Skin Cancer","gt_translate_keys":[{"key":"rendered","format":"text"}]},"content":{"rendered":"<h4>Words like dysplastic nevus and metastasis are not words that you use every day and can be worrisome when you hear them used in your dermatologist\u2019s office.<\/h4>\n<p>To help you navigate some of the complex terms associated with <a href=\"https:\/\/www.skincancer.org\/skin-cancer-information\/\">skin cancer<\/a>, we&#8217;ve compiled an easy-to-follow glossary of definitions.<\/p>\n<p><strong>Actinic keratosis (AK) <\/strong>\u2013 The most common type of precancerous skin lesion. <a href=\"https:\/\/www.skincancer.org\/skin-cancer-information\/actinic-keratosis\/\">Actinic keratoses<\/a> appear on skin that has been frequently exposed to <a href=\"https:\/\/www.skincancer.org\/risk-factors\/uv-radiation\/\">ultraviolet (UV) radiation<\/a> from the sun or to artificial sources of UV light, such as\u00a0<a href=\"https:\/\/www.skincancer.org\/risk-factors\/tanning\/\">indoor tanning<\/a> beds. They typically look like crusty or scaly skin patches.<\/p>\n<p><strong>Acral lentiginous melanoma <\/strong>\u2013 A rare type of <a href=\"https:\/\/www.skincancer.org\/skin-cancer-information\/melanoma\/\">melanoma<\/a> that often arises on the palms of the hands, the soles of the feet or under the nails. The most common type of melanoma diagnosed in <a href=\"https:\/\/www.skincancer.org\/skin-cancer-information\/skin-cancer-skin-of-color\/\">people of color<\/a>, it is an especially aggressive form of the disease that is not caused by ultraviolet exposure.<\/p>\n<p><strong>Atypical moles<\/strong>\u2013 Unusual-looking benign moles, also known as <a href=\"https:\/\/www.skincancer.org\/risk-factors\/atypical-moles\/\">dysplastic nevi<\/a>, these lesions often resemble melanoma. <a href=\"http:\/\/www.skincancer.org\/skin-cancer-information\/melanoma\/melanoma-warning-signs-and-images\/do-you-know-your-abcdes\">Like melanoma<\/a>, they are often over 6 mm (1\/4\u201d) in diameter, are asymmetrical and have irregular borders and more than one color. People with atypical moles are at increased risk of developing melanoma, either directly in the moles or elsewhere on the body.<\/p>\n<p><strong>Basal cell carcinoma (BCC) <\/strong>\u2013 The most common form of skin cancer, these tumors develop in the skin\u2019s basal cells, which line the deepest layer of the epidermis \u2013 the outermost layer of your skin. Caused mainly by a combination of cumulative and intense, occasional sun exposure, <a href=\"https:\/\/www.skincancer.org\/skin-cancer-information\/basal-cell-carcinoma\/\">BCCs<\/a> often look like open sores, red patches, pink growths, shiny bumps or scars. BCCs rarely spread to other parts of the body, but if not caught early, they can be extremely destructive and even disfiguring where they occur, sometimes costing someone an eye, ear or nose.<\/p>\n<p><strong>Benign <\/strong>\u2013 When you hear this, it\u2019s usually good news. Benign tumors are noncancerous growths and do not spread to other parts of the body. Depending on the nature of the benign tumor \u2013 whether it is cosmetically acceptable, interferes with function or potentially can turn cancerous \u2013 it may or may not be necessary to remove.<\/p>\n<p><strong>Biopsy <\/strong>\u2013 A procedure done in a dermatologist\u2019s office to study a suspicious growth at the cellular level. The physician <a href=\"https:\/\/www.skincancer.org\/blog\/you-need-a-biopsy-now-what-happens-part-1\/\">removes a small sample of the lesion<\/a> and has it <a href=\"https:\/\/www.skincancer.org\/blog\/you-need-a-biopsy-now-what-happens-part-2\/\">examined in the lab<\/a> to determine what kind of growth it is and whether it is cancerous or benign.<\/p>\n<p><strong>Dermis <\/strong>\u2013 Did you know skin is the heaviest organ in the body, weighing twice as much as the brain? The dermis is the second major layer of skin, containing our blood capillaries, nerve endings, sweat glands, hair follicles and other structures. Here are <a title=\"https:\/\/www.skincancer.org\/blog\/10-surprising-things-about-your-skin\/\" href=\"https:\/\/www.skincancer.org\/blog\/10-surprising-things-about-your-skin\/\">10 surprising things about your skin<\/a>.<\/p>\n<p><strong>Dysplastic nevus &#8211;<\/strong>\u00a0Also known as an\u00a0<a href=\"https:\/\/www.skincancer.org\/risk-factors\/atypical-moles\/\">atypical mole<\/a>, a\u00a0dysplastic nevus is am unusual-looking mole that has irregular features under the microscope. While benign, this type of mole is important to keep an eye on. Individuals with atypical moles are at increased risk for <a href=\"http:\/\/skincancer.org\/skin-cancer-information\/melanoma\/\">melanoma<\/a>, a dangerous skin cancer.<\/p>\n<p><strong>Epidermis <\/strong>\u2013 As humans, we shed a lot! Your skin renews itself every 28 days with an average of 40,000 dead skin cells being shed per minute. The outermost layer of the skin, the epidermis is made up of mostly scale-like cells known as squamous cells. Most skin cancers begin in the epidermis.<\/p>\n<p><strong>In situ <\/strong>\u2013 Latin for \u201cin place,\u201d this typically means good news since it refers to a cancerous but noninvasive tumor that has not penetrated beyond the epidermis into the dermis. But even skin cancers diagnosed in the early stages can be painful or <a title=\"https:\/\/www.skincancer.org\/blog\/ask-the-expert-can-i-avoid-a-scar\/\" href=\"https:\/\/www.skincancer.org\/blog\/ask-the-expert-can-i-avoid-a-scar\/\">cause scarring<\/a>\u00a0and may require multiple treatments. In situ skin cancers can also become invasive if not removed in a timely way.<\/p>\n<p><strong>Invasive <\/strong>\u2013 An invasive skin cancer has penetrated beyond the epidermis into the dermis and is growing into surrounding, healthy tissue. Invasive skin cancers should be removed promptly, and tests need to be done to see if further treatments are called for.<\/p>\n<p><strong>Lesion <\/strong>\u2013 A skin lesion is an abnormal mark or growth on the skin. It can range from a blister, birthmark, scar or benign nodule to a serious skin cancer.<\/p>\n<p><strong>Lymph nodes <\/strong>\u2013 These small, bean-sized glands throughout the body, part of the lymphatic system, are major sites for the lymphocytes and other white blood cells, which engulf and destroy foreign particles such as bacteria. Important for proper immune functioning, the lymphatic system delivers nutrients throughout the body via the lymphatic fluid and acts as a filter by carrying\u00a0waste products to the bloodstream and ultimately out of the body. However, cancer cells can also use this system to travel throughout the body, attacking distant sites and organs.<\/p>\n<p><strong>Malignant <\/strong>\u2013 Another word for cancerous. Malignant tumors consist of abnormal cells that divide without control and can invade nearby healthy tissues.<\/p>\n<p><strong>Melanocyte <\/strong>\u2013 Specialized skin cells that produce the protective skin-darkening pigment melanin. Exposure to <a href=\"https:\/\/www.skincancer.org\/risk-factors\/uv-radiation\/\">UV radiation<\/a> damages melanocytes, causing sunburns and tanning, which can lead to melanoma.<\/p>\n<p><strong>Melanoma <\/strong>\u2013 A cancer that arises from damaged or defective melanocytes. One of the most dangerous forms of skin cancer, <a href=\"https:\/\/www.skincancer.org\/skin-cancer-information\/melanoma\/\">melanoma<\/a> is often triggered by the kind of intense, intermittent sun exposure that leads to sunburn.<\/p>\n<p><strong>Merkel cell carcinoma (MCC) <\/strong>\u2013 A<a href=\"https:\/\/www.skincancer.org\/skin-cancer-information\/rare-skin-cancers\/\"> rare type of skin\u00a0cancer\u00a0<\/a>that usually appears as a flesh-colored or bluish-red nodule, often on the face, head or neck. If not caught very early,<a href=\"https:\/\/www.skincancer.org\/skin-cancer-information\/merkel-cell-carcinoma\/\"> MCC<\/a> is an exceptionally dangerous skin cancer. \u00a0Like most skin cancers, it is most often caused by sun exposure. A specific type of virus called a polyomavirus is also involved in the majority of MCCs.<\/p>\n<p><strong>Metastasis <\/strong>\u2013 The spread of cancer cells from a primary tumor to new areas of the body (often by way of the lymph system or bloodstream). Once a tumor has metastasized to the lymph nodes, it is considered a stage III cancer. Once it has metastasized to distant body sites and organs, it is considered stage IV.<\/p>\n<p><strong>Mole <\/strong>\u2013 A pigmented spot, mark or growth on the body. Almost everyone has at least one mole, if not multiple moles. They occur when cells in the skin grow in a cluster. Most moles are benign, but those that exhibit any abnormal, <a href=\"https:\/\/www.skincancer.org\/risk-factors\/atypical-moles\/\">atypical<\/a> or changing features are typically monitored closely by dermatologists to ensure they are not cancers.<\/p>\n<p><strong>Squamous cell carcinoma (SCC)\u00a0<\/strong>\u2013 The second most common form of skin cancer, these tumors develop from abnormal squamous cells, which compose most of the epidermis. <a href=\"https:\/\/www.skincancer.org\/skin-cancer-information\/squamous-cell-carcinoma\/\">SCC<\/a>s often look like scaly red patches, open sores, warts or elevated growths with a central depression. They may crust or bleed. They can become disfiguring and sometimes deadly if not caught early.<\/p>\n<p><strong>Staging \u2013 <\/strong>Staging is a numerical system used in cancer diagnosis to sum up how far a cancer has advanced. For example, stage I means the cancer is small and contained, with no high-risk features; in stage II, the cancer still has not spread, but is large or has other features that put it at high risk of spreading to the nearby lymph nodes; in stage III, the cancer has spread to the lymph nodes or has gone beyond the primary tumor en route to the lymph nodes; and in stage IV, it has spread to distant body sites or organs. Any tumor beyond stage I brings increased risk, and stage III and IV tumors can be life-threatening. The staging system was put in place to help doctors and other caregivers home in on the patient\u2019s prognosis and the best treatment options.<\/p>\n<p><strong>Subungual melanoma<\/strong> \u2013 <a href=\"https:\/\/www.skincancer.org\/blog\/looking-for-clues-the-lesser-known-signs-of-skin-cancer\/\">Subungual melanoma<\/a> is a rare, potentially deadly form of melanoma that is more common in <a href=\"https:\/\/www.skincancer.org\/skin-cancer-information\/skin-cancer-skin-of-color\/\">people of color<\/a>. It appears as a brown or black streak under a fingernail or a toenail, but often increases in size.<\/p>\n<p><strong>Tumor <\/strong>\u2013 A mass in the body caused by abnormal growth and clustering of tissue. Tumors can be either benign or malignant, and often may require a biopsy or other medical testing to determine which it is and exactly what it is.<\/p>\n","protected":false,"gt_translate_keys":[{"key":"rendered","format":"html"}]},"excerpt":{"rendered":"<p>Words like dysplastic nevus and metastatic are not words that you hear every day and can be worrisome when you hear them used in your dermatologist\u2019s office. <\/p>\n","protected":false,"gt_translate_keys":[{"key":"rendered","format":"html"}]},"author":1,"featured_media":1784,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[10,5673],"tags":[14,9,5183,12],"class_list":["post-1576","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-skin-cancer-information","category-skin-of-color","tag-basal-cell-carcinoma","tag-melanoma","tag-people-of-color","tag-squamous-cell-carcinoma"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v25.3 (Yoast SEO v25.3) - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Defining Skin Cancer<\/title>\n<meta name=\"description\" content=\"To help you navigate some of the complex terms associated with skin cancer, we&#039;ve compiled an easy-to-follow glossary of definitions.\" \/>\n<meta name=\"robots\" content=\"index, follow, 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