{"id":2121,"date":"2019-06-05T16:23:31","date_gmt":"2019-06-05T16:23:31","guid":{"rendered":"http:\/\/scfredesignpro.wpengine.com\/?page_id=2121"},"modified":"2025-04-18T17:40:10","modified_gmt":"2025-04-18T17:40:10","slug":"scc-treatment-options","status":"publish","type":"page","link":"https:\/\/www.skincancer.org\/skin-cancer-information\/squamous-cell-carcinoma\/scc-treatment-options\/","title":{"rendered":"Squamous Cell Carcinoma Treatment"},"content":{"rendered":"<div class=\"wpb-content-wrapper\"><p>[vc_section][vc_row][vc_column][vc_column_text el_class=&#8221;small translation&#8221;]<\/p>\n<p style=\"text-align: right;\">Translation:\u00a0\u00a0 <a href=\"https:\/\/skincancer.org\/international\/le-carcinome-epidermoide-cutane\/#treatment\"><img loading=\"lazy\" decoding=\"async\" class=\"size-full wp-image-2507\" src=\"https:\/\/skincancer.org\/wp-content\/uploads\/france-flag-icon-16.png\" alt=\"\" width=\"16\" height=\"11\" \/><\/a>\u00a0<a href=\"http:\/\/skincancer.org\/international\/das-plattenepithelkarzinom\/#treatment\"><img loading=\"lazy\" decoding=\"async\" class=\"size-medium wp-image-2508\" src=\"https:\/\/skincancer.org\/wp-content\/uploads\/germany-flag-icon-16.png\" alt=\"\" width=\"16\" height=\"10\" \/><\/a>\u00a0<a href=\"http:\/\/skincancer.org\/international\/carcinoma-spino-cellulare\/#treatment\"><img loading=\"lazy\" decoding=\"async\" class=\"size-medium wp-image-2509\" src=\"https:\/\/skincancer.org\/wp-content\/uploads\/italy-flag-icon-16.png\" alt=\"\" width=\"16\" height=\"11\" \/><\/a> <a href=\"https:\/\/www.skincancer.org\/international\/%CE%B1%CE%BA%CE%B1%CE%BD%CE%B8%CE%BF%CE%BA%CF%85%CF%84%CF%84%CE%B1%CF%81%CE%B9%CE%BA%CE%BF-%CE%BA%CE%B1%CF%81%CE%BA%CE%B9%CE%BD%CF%89%CE%BC%CE%B1\/\"><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-4172\" src=\"https:\/\/www.skincancer.org\/wp-content\/uploads\/greece-flag-icon-16.png\" alt=\"\" width=\"16\" height=\"11\" \/><\/a> <a href=\"https:\/\/www.skincancer.org\/international\/carcinoma-celulas-escamosas\/\"><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-4187\" src=\"https:\/\/www.skincancer.org\/wp-content\/uploads\/portugal-flag-icon-16.png\" alt=\"\" width=\"16\" height=\"11\" \/><\/a><\/p>\n<p style=\"text-align: right;\"><a href=\"https:\/\/www.skincancer.org\/international\/carcinoma-de-celulas-escamosas\/#treatment\">En Espa\u00f1ol<\/a><\/p>\n<p>[\/vc_column_text][vc_column_text]<\/p>\n<h1 style=\"text-align: center;\">Squamous Cell Carcinoma\u00a0<span style=\"color: rgba(50,63,74,0.65);\">Treatment<\/span><\/h1>\n<p>[\/vc_column_text][\/vc_column][\/vc_row][vc_row][vc_column offset=&#8221;vc_col-lg-offset-1 vc_col-lg-10&#8243;][vc_custom_heading text=&#8221;Effective Treatment Options for Early Stage SCC&#8221; font_container=&#8221;tag:h2|text_align:center&#8221; use_theme_fonts=&#8221;yes&#8221; css=&#8221;&#8221;][\/vc_column][\/vc_row][\/vc_section][vc_section][vc_row][vc_column width=&#8221;9\/12&#8243;][vc_column_text el_class=&#8221;large&#8221;]Most squamous cell carcinomas (SCCs) of the skin can be cured when found and treated early. Treatment should happen as soon as possible after diagnosis, since more advanced SCCs of the skin are more difficult to treat and can become dangerous, spreading to local lymph nodes, distant tissues and organs. Find out more about treatment options for <a href=\"http:\/\/skincancer.org\/skin-cancer-information\/squamous-cell-carcinoma\/advanced-scc\/\">advanced or recurring SCCs here<\/a>.<\/p>\n<p>If you\u2019ve been diagnosed with an SCC that has not spread (in situ), there are several effective treatments that can usually be performed on an outpatient basis. The choices available to you depend on the tumor type, size, location and depth, as well as your age and overall health.<\/p>\n<p>Options include:<\/p>\n<ul>\n<li><a href=\"#excisional\">Excisional surgery<\/a><\/li>\n<li><a href=\"#mohs\">Mohs surgery<\/a><\/li>\n<li><a href=\"#cryosurgery\">Cryosurgery<\/a><\/li>\n<li><a href=\"#curettage\">Curettage and electrodesiccation (electrosurgery)<\/a><\/li>\n<li><a href=\"#laser\">Laser surgery<\/a><\/li>\n<li><a href=\"#radiation\">Radiation<\/a><\/li>\n<li><a href=\"#photodynamic\">Photodynamic therapy (PDT)<\/a><\/li>\n<li><a href=\"#topical\">Topical medications<\/a><\/li>\n<\/ul>\n<p>Ask your dermatologist to clearly explain the options that might work best for you, including details about the risks and benefits. Check our treatment glossary for more detailed information.[\/vc_column_text][\/vc_column][vc_column width=&#8221;1\/4&#8243;][vc_single_image image=&#8221;548&#8243;][\/vc_column][\/vc_row][\/vc_section][vc_section full_width=&#8221;stretch_row&#8221; content_placement=&#8221;middle&#8221; css=&#8221;.vc_custom_1532456871168{background-color: #323f4a !important;}&#8221;][vc_row][vc_column width=&#8221;1\/4&#8243; el_class=&#8221;subpage-nav&#8221;][vc_btn title=&#8221;Overview&#8221; style=&#8221;custom&#8221; custom_background=&#8221;#323f4a&#8221; custom_text=&#8221;#ffcc42&#8243; shape=&#8221;square&#8221; size=&#8221;lg&#8221; align=&#8221;center&#8221; i_align=&#8221;right&#8221; i_icon_fontawesome=&#8221;fa fa-arrow-right&#8221; add_icon=&#8221;true&#8221; link=&#8221;url:http%3A%2F%2Fwww.skincancer.org%2Fskin-cancer-information%2Fsquamous-cell-carcinoma%2F|title:Squamous%20Cell%20Carcinoma||&#8221;][\/vc_column][vc_column width=&#8221;1\/4&#8243; el_class=&#8221;subpage-nav&#8221;][vc_btn title=&#8221;Warning Signs&#8221; style=&#8221;custom&#8221; custom_background=&#8221;#323f4a&#8221; custom_text=&#8221;#ffcc42&#8243; shape=&#8221;square&#8221; size=&#8221;lg&#8221; align=&#8221;center&#8221; i_align=&#8221;right&#8221; i_icon_fontawesome=&#8221;fa fa-arrow-right&#8221; add_icon=&#8221;true&#8221; link=&#8221;url:http%3A%2F%2Fwww.skincancer.org%2Fskin-cancer-information%2Fsquamous-cell-carcinoma%2Fscc-warning-signs-and-images%2F|title:Squamous%20Cell%20Carcinoma%20Warning%20Signs||&#8221;][\/vc_column][vc_column width=&#8221;1\/4&#8243; el_class=&#8221;subpage-nav&#8221;][vc_btn title=&#8221;Risk Factors&#8221; style=&#8221;custom&#8221; custom_background=&#8221;#323f4a&#8221; custom_text=&#8221;#ffcc42&#8243; shape=&#8221;square&#8221; size=&#8221;lg&#8221; align=&#8221;center&#8221; i_align=&#8221;right&#8221; i_icon_fontawesome=&#8221;fa fa-arrow-right&#8221; add_icon=&#8221;true&#8221; link=&#8221;url:http%3A%2F%2Fwww.skincancer.org%2Fskin-cancer-information%2Fsquamous-cell-carcinoma%2Fscc-causes-and-risk-factors%2F|title:Squamous%20Cell%20Carcinoma%20Risk%20Factors||&#8221;][\/vc_column][vc_column width=&#8221;1\/4&#8243; el_class=&#8221;subpage-nav&#8221;][vc_btn title=&#8221;Advanced Treatment&#8221; style=&#8221;custom&#8221; custom_background=&#8221;#323f4a&#8221; custom_text=&#8221;#ffcc42&#8243; shape=&#8221;square&#8221; size=&#8221;lg&#8221; align=&#8221;center&#8221; i_align=&#8221;right&#8221; i_icon_fontawesome=&#8221;fa fa-arrow-right&#8221; add_icon=&#8221;true&#8221; link=&#8221;url:http%3A%2F%2Fwww.skincancer.org%2Fskin-cancer-information%2Fsquamous-cell-carcinoma%2Fadvanced-scc%2F|title:Advanced%20Squamous%20Cell%20Carcinoma%20Treatment||&#8221;][\/vc_column][\/vc_row][\/vc_section][vc_section][vc_row el_class=&#8221;content-block&#8221; el_id=&#8221;excisional&#8221;][vc_column width=&#8221;1\/3&#8243;][vc_custom_heading text=&#8221;Excisional surgery&#8221; font_container=&#8221;tag:h3|text_align:left&#8221; use_theme_fonts=&#8221;yes&#8221;][\/vc_column][vc_column width=&#8221;2\/3&#8243;][vc_column_text]<\/p>\n<h4>How it works<\/h4>\n<p>Using a scalpel, the surgeon removes the entire tumor along with a \u201csafety margin\u201d of surrounding normal tissue. The margin of normal skin removed depends on the thickness and location of the tumor.<\/p>\n<p>Typically, the patient goes home after the surgery, and the excised tumor goes to the lab. If the lab finds cancer cells beyond the margins, the patient may need to return for more surgery until margins are cancer-free.<\/p>\n<h4>When it&#8217;s used<\/h4>\n<p>For small, early SCCs that have not spread, excisional surgery is frequently the only treatment required.[\/vc_column_text][\/vc_column][\/vc_row][vc_row el_class=&#8221;content-block&#8221; el_id=&#8221;mohs&#8221;][vc_column width=&#8221;1\/3&#8243;][vc_custom_heading text=&#8221;Mohs surgery&#8221; font_container=&#8221;tag:h3|text_align:left&#8221; use_theme_fonts=&#8221;yes&#8221;][\/vc_column][vc_column width=&#8221;2\/3&#8243;][vc_column_text]<\/p>\n<h4>How it works<\/h4>\n<p><a href=\"https:\/\/www.skincancer.org\/treatment-resources\/mohs-surgery\/\">Mohs surgery<\/a> is performed during a single visit, in stages. The surgeon removes the visible tumor and a very small margin of tissue around and beneath the tumor site. The surgeon color-codes the tissue and draws a map correlated to the patient\u2019s surgical site. In an on-site lab, the surgeon examines the tissue under a microscope to see if any cancer cells remain. If so, the surgeon returns to the patient and removes more tissue exactly where the cancer cells are. The doctor repeats this process until there is no evidence of cancer. Then the wound may be closed or, in some cases, allowed to heal on its own.<\/p>\n<h4>When it&#8217;s used<\/h4>\n<p>Mohs surgery is the <a href=\"http:\/\/www.skincancer.org\/treatment-resources\/mohs-surgery\/mohs-the-gold-standard\/\">most effective technique<\/a> for removing SCCs, sparing the greatest amount of healthy tissue while achieving the highest possible cure rate \u2013 up to 97 percent for tumors treated for the first time. It is often recommended for SCCs located in small, cosmetically or functionally important areas around the eyes, nose, lips, ears, scalp, fingers, toes or genitals. Mohs is also used for SCCs that have recurred, and for tumors that are large or growing rapidly, as well as ones with indistinct edges.\u00a0<a href=\"http:\/\/skincancer.org\/treatment-resources\/mohs-surgery\/\">Learn if Mohs is right for you.<\/a><\/p>\n<h4>Superficial versus minimally invasive<\/h4>\n<p>Superficial SCCs have not penetrated (or invaded) below the topmost layer of the skin (the epidermis), while minimally invasive SCCs have just barely invaded the second layer of skin (the dermis) and have no high-risk characteristics.[\/vc_column_text][\/vc_column][\/vc_row][vc_row el_class=&#8221;content-block&#8221; el_id=&#8221;curettage&#8221;][vc_column width=&#8221;1\/3&#8243;][vc_custom_heading text=&#8221;Curettage and electrodesiccation (electrosurgery)&#8221; font_container=&#8221;tag:h3|text_align:left&#8221; use_theme_fonts=&#8221;yes&#8221;][\/vc_column][vc_column width=&#8221;2\/3&#8243;][vc_column_text]<\/p>\n<h4>How it works<\/h4>\n<p>The physician scrapes or shaves off the SCC with a curette (a sharp instrument with a ring-shaped tip), then uses heat or a chemical agent to stop the bleeding and destroy remaining cancer cells.\u00a0 The procedure may be repeated a few times during the same session until no cancer cells remain.<\/p>\n<h4>When it&#8217;s used<\/h4>\n<p><a href=\"http:\/\/skincancer.org\/treatment-resources\/treatment-glossary\/#curettage-electrodesiccation\">Curettage and electrodesiccation<\/a> can be effective for most small, superficial or minimally invasive SCCs.[\/vc_column_text][\/vc_column][\/vc_row][vc_row el_class=&#8221;content-block&#8221; el_id=&#8221;cryosurgery&#8221;][vc_column width=&#8221;1\/3&#8243;][vc_custom_heading text=&#8221;Cryosurgery&#8221; font_container=&#8221;tag:h3|text_align:left&#8221; use_theme_fonts=&#8221;yes&#8221;][\/vc_column][vc_column width=&#8221;2\/3&#8243;][vc_column_text]<\/p>\n<h4>How it works<\/h4>\n<p>The physician uses a cotton-tipped applicator or spray device to apply liquid nitrogen to freeze and destroy the tumor, which eventually falls off, allowing healthy skin to emerge.<\/p>\n<h4>When it&#8217;s used<\/h4>\n<p><a href=\"http:\/\/skincancer.org\/treatment-resources\/treatment-glossary\/#cryosurgery\">Cryosurgery<\/a> is effective for superficial SCCs, especially for patients with bleeding disorders, implantable cardiac devices or problems tolerating anesthesia.[\/vc_column_text][\/vc_column][\/vc_row][vc_row el_class=&#8221;content-block&#8221; el_id=&#8221;laser&#8221;][vc_column width=&#8221;1\/3&#8243;][vc_custom_heading text=&#8221;Laser surgery&#8221; font_container=&#8221;tag:h3|text_align:left&#8221; use_theme_fonts=&#8221;yes&#8221;][\/vc_column][vc_column width=&#8221;2\/3&#8243;][vc_column_text]<\/p>\n<h4>How it works<\/h4>\n<p>The physician directs a beam of intense light at the tumor to target the cancerous cells. Some lasers vaporize (ablate) the skin cancer, while others (nonablative lasers) convert the beam of light to heat, which destroys the tumor.<\/p>\n<h4>When it&#8217;s used<\/h4>\n<p><a href=\"http:\/\/skincancer.org\/treatment-resources\/treatment-glossary\/#laser-surgery\">Laser surgery<\/a> is not yet FDA-approved for SCC but is sometimes used for superficial SCCs, especially when other techniques have been unsuccessful.[\/vc_column_text][\/vc_column][\/vc_row][vc_row el_class=&#8221;content-block&#8221; el_id=&#8221;radiation&#8221;][vc_column width=&#8221;1\/3&#8243;][vc_custom_heading text=&#8221;Radiation&#8221; font_container=&#8221;tag:h3|text_align:left&#8221; use_theme_fonts=&#8221;yes&#8221;][\/vc_column][vc_column width=&#8221;2\/3&#8243;][vc_column_text]<\/p>\n<h4>How it works<\/h4>\n<p>The physician uses low-energy X-ray beams to destroy the tumor, with no need for cutting or anesthesia. Destruction of the tumor may require several treatments over a few weeks or daily treatments for a specified time.<\/p>\n<h4>When it&#8217;s used<\/h4>\n<p><a href=\"http:\/\/skincancer.org\/treatment-resources\/treatment-glossary\/#radiation-therapy\">Radiation therapy<\/a> is primarily used for SCCs that are hard to treat surgically, and in elderly patients or people in poor health for whom surgery is not advised. For some cases of advanced SCC, especially those with perineural involvement, radiation may be used after surgery, or in combination with other treatments.[\/vc_column_text][\/vc_column][\/vc_row][vc_row el_class=&#8221;content-block&#8221; el_id=&#8221;photodynamic&#8221;][vc_column width=&#8221;1\/3&#8243;][vc_custom_heading text=&#8221;Photodynamic therapy (PDT)&#8221; font_container=&#8221;tag:h3|text_align:left&#8221; use_theme_fonts=&#8221;yes&#8221;][\/vc_column][vc_column width=&#8221;2\/3&#8243;][vc_column_text css=&#8221;&#8221;]<\/p>\n<h4>How it works<\/h4>\n<p><span class=\"TextRun SCXW189564640 BCX0\" lang=\"EN-US\" xml:lang=\"EN-US\" data-contrast=\"none\"><span class=\"NormalTextRun SCXW189564640 BCX0\">The physician applies a light-sensitizing topical agent and, after allowing <\/span><span class=\"NormalTextRun SCXW189564640 BCX0\">a period of time<\/span><span class=\"NormalTextRun SCXW189564640 BCX0\"> for absorption, <\/span><\/span><span class=\"TextRun Highlight SCXW189564640 BCX0\" lang=\"EN-US\" xml:lang=\"EN-US\" data-contrast=\"none\"><span class=\"NormalTextRun SCXW189564640 BCX0\">directs a strong red or blue light or a pulsed-dye laser at the tumor<\/span><\/span><span class=\"TextRun SCXW189564640 BCX0\" lang=\"EN-US\" xml:lang=\"EN-US\" data-contrast=\"none\"><span class=\"NormalTextRun SCXW189564640 BCX0\"> to activate the topical agent, killing cancer cells while sparing healthy tissue.<\/span> <span class=\"NormalTextRun SCXW189564640 BCX0\">After the procedure, patients must strictly avoid sunlight and indoor tanning for at least 48 hours, as ultraviolet exposure will increase activation of the medication and may cause severe sunburns.<\/span><\/span><span class=\"EOP SCXW189564640 BCX0\" data-ccp-props=\"{}\">\u00a0<\/span><\/p>\n<h4>When it&#8217;s used<\/h4>\n<p><a href=\"http:\/\/skincancer.org\/treatment-resources\/treatment-glossary\/#photodynamic-therapy\">PDT<\/a> can be used for some superficial SCCs on the face and scalp but is not recommended for invasive SCCs. It is most effective for treating actinic keratoses, which can be precursor lesions to SCC.[\/vc_column_text][\/vc_column][\/vc_row][vc_row el_class=&#8221;content-block&#8221; el_id=&#8221;topical&#8221;][vc_column width=&#8221;1\/3&#8243;][vc_custom_heading text=&#8221;Topical medications&#8221; font_container=&#8221;tag:h3|text_align:left&#8221; use_theme_fonts=&#8221;yes&#8221;][\/vc_column][vc_column width=&#8221;2\/3&#8243;][vc_column_text]<\/p>\n<h4>How it works<\/h4>\n<p><a href=\"http:\/\/skincancer.org\/treatment-resources\/treatment-glossary\/#5-fluorouracil\">5-fluorouracil (5-FU)<\/a>\u00a0and\u00a0<a href=\"http:\/\/skincancer.org\/treatment-resources\/treatment-glossary\/#imiquimod\">imiquimod<\/a>\u00a0are creams or gels that can be applied directly to affected areas of the skin to treat superficial SCCs with minimal risk of scarring. Imiquimod activates the immune system to attack cancerous cells, while 5-FU is a topical therapy that targets cancerous and precancerous cells.<\/p>\n<h4>When it&#8217;s used<\/h4>\n<p>While these topical medications are not yet FDA-approved for treating SCCs, they are\u00a0sometimes used for superficial tumors. The medications are also used preventatively for AKs.<\/p>\n<h4>Treating advanced SCCs<\/h4>\n<p>More extensive treatment is necessary for SCCs that have spread, are large in size, have penetrated the skin deeply and caused severe local damage or have resisted multiple treatments and recurred. Find out more about these <a href=\"http:\/\/skincancer.org\/skin-cancer-information\/squamous-cell-carcinoma\/advanced-scc\/\">treatment options<\/a> here.[\/vc_column_text][\/vc_column][\/vc_row][\/vc_section][vc_row][vc_column][vc_column_text css=&#8221;&#8221;]<em><strong>Reviewed by:<\/strong><br \/>\nElizabeth K. Hale, MD<br \/>\nC. William Hanke, MD<\/em><\/p>\n<p><b>Note:<\/b>\u00a0The information included on this website is medically reviewed and factually accurate. It is intended for educational purposes only. The treatment information on this page is not a recommendation or endorsement of any drug, device or treatment, nor does it suggest that any drug, device or treatment is safe or effective for you. If you have any questions about skin cancer treatments, please talk to your health care provider.[\/vc_column_text][\/vc_column][\/vc_row][vc_row][vc_column][vc_row_inner el_class=&#8221;spons-row&#8221;][vc_column_inner][vc_column_text]<\/p>\n<p style=\"text-align: center;\">This section made possible with support from<\/p>\n<p>[\/vc_column_text][vc_column_text css=&#8221;&#8221;]<\/p>\n<div style=\"display: flex; justify-content: center; align-items: center; gap: 10px;\"><a class=\"sponsor-logo\" href=\"https:\/\/mysccskincancer.com\/\" target=\"_blank\" rel=\"noopener\"><br \/>\n<img decoding=\"async\" class=\"size-full aligncenter\" src=\"https:\/\/www.skincancer.org\/wp-content\/uploads\/CastleLogoColor_Transparent.png\" alt=\"Castle Biosciences Logo\" \/><br \/>\n<\/a><a class=\"sponsor-logo\" href=\"https:\/\/www.regeneron.com\/\" target=\"_blank\" rel=\"noopener\"><br \/>\n<img loading=\"lazy\" decoding=\"async\" class=\"size-medium wp-image-7840 aligncenter\" src=\"https:\/\/www.skincancer.org\/wp-content\/uploads\/Regeneron-Logo-No-Tagline-copy-600x95.png\" sizes=\"auto, (max-width: 600px) 100vw, 600px\" srcset=\"https:\/\/www.skincancer.org\/wp-content\/uploads\/\/Regeneron-Logo-No-Tagline-copy-600x95.png 600w, https:\/\/www.skincancer.org\/wp-content\/uploads\/\/Regeneron-Logo-No-Tagline-copy-768x121.png 768w, https:\/\/www.skincancer.org\/wp-content\/uploads\/\/Regeneron-Logo-No-Tagline-copy.png 800w\" alt=\"\" width=\"600\" height=\"95\" \/><br \/>\n<\/a><\/div>\n<p>[\/vc_column_text][\/vc_column_inner][\/vc_row_inner][\/vc_column][\/vc_row]<\/p>\n<\/div>","protected":false},"excerpt":{"rendered":"<p>Find out about squamous cell carcinoma treatment options for early stage skin cancer. Treatment should happen soon after diagnosis.<\/p>\n","protected":false},"author":1,"featured_media":548,"parent":2109,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"footnotes":""},"class_list":["post-2121","page","type-page","status-publish","has-post-thumbnail","hentry"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v25.3 (Yoast SEO v25.3) - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Squamous Cell Carcinoma Treatment - The Skin Cancer Foundation<\/title>\n<meta name=\"description\" content=\"Find out about squamous cell carcinoma treatment options for early stage skin cancer. 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