{"id":3961,"date":"2021-03-31T15:17:56","date_gmt":"2021-03-31T15:17:56","guid":{"rendered":"http:\/\/scfredesignpro.wpengine.com\/?p=3961"},"modified":"2025-01-17T20:26:16","modified_gmt":"2025-01-17T20:26:16","slug":"amelanotic-melanoma-it-doesnt-look-like-other-melanomas","status":"publish","type":"post","link":"https:\/\/www.skincancer.org\/blog\/amelanotic-melanoma-it-doesnt-look-like-other-melanomas\/","title":{"rendered":"Amelanotic Melanoma: It Doesn\u2019t Look Like Other Melanomas","gt_translate_keys":[{"key":"rendered","format":"text"}]},"content":{"rendered":"<p>Odds are, if you have spent time on <a href=\"https:\/\/www.skincancer.org\">SkinCancer.org<\/a>, you know the classic ABCDE <a href=\"https:\/\/www.skincancer.org\/skin-cancer-information\/melanoma\/melanoma-warning-signs-and-images\/\" rel=\"noopener noreferrer\">warning signs of melanoma:<\/a>\u00a0<strong>A<\/strong>symmetry,\u00a0<strong>B<\/strong>order irregularity,\u00a0<strong>C<\/strong>olor variations,\u00a0<strong>D<\/strong>iameter over \u00bc inch (6 mm) or <strong>D<\/strong>ark in color, and\u00a0<strong>E<\/strong>volution or change. But did you know that some melanomas have very different features?<\/p>\n<p>For example, certain melanomas may have no color at all. Physicians refer to these as \u201camelanotic\u201d melanomas, because they are conspicuously missing melanin, the dark pigment that gives most moles and melanomas their color. These unpigmented melanomas may be pinkish-looking, reddish, purple, normal skin color or essentially clear and colorless.<\/p>\n<div id=\"metaslider-id-3968\" style=\"max-width: 340px; margin: 0 auto;\" class=\"ml-slider-3-99-0 ml-slider-pro-2-47-0 metaslider metaslider-responsive metaslider-3968 ml-slider ms-theme-_theme_1565755722\" role=\"region\" aria-label=\"Amelanotic\" data-width=\"340\">\n    <div id=\"metaslider_container_3968\">\n        <ul id='metaslider_3968' class='rslides'>\n            <li aria-roledescription='slide' aria-labelledby='slide-0'><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/www.skincancer.org\/wp-content\/uploads\/leg-amelanotic-melanoma-340x340.jpg\" height=\"340\" width=\"340\" alt=\"An example of a flat, amelanotic, superficial spreading melanoma on the leg.\" class=\"slider-3968 slide-3969 msDefaultImage\" title=\"melanoma on leg\" \/><div class=\"caption-wrap\"><div class=\"caption\">Amelanotic melanomas may be pinkish-looking, reddish, purple, normal skin color or essentially clear and colorless.<\/div><\/div><\/li>\n            <li style='display: none;' aria-roledescription='slide' aria-labelledby='slide-1'><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/www.skincancer.org\/wp-content\/uploads\/amelanotic-melanoma-scalp-crop-318x318.png\" height=\"340\" width=\"340\" alt=\"A nodular melanoma developing within an amelanotic melanoma in situ on the scalp.\" class=\"slider-3968 slide-3970 msDefaultImage\" title=\"amelanotic-melanoma-scalp-crop\" \/><div class=\"caption-wrap\"><div class=\"caption\">Amelanotic melanoma.<\/div><\/div><\/li>\n        <\/ul>\n        \n    <\/div>\n<\/div>\n<hr \/>\n<p>The problem is, patients and even physicians may not immediately recognize these as possible melanomas. Even today\u2019s specialized computer apps for early melanoma recognition tend to be modeled on the classic ABCDEs and can miss more clinically subtle melanomas like these. Amelanotic melanomas can resemble other skin cancers like basal cell or squamous cell carcinoma, or worse, may be mistaken for benign moles, scars or cysts. This can delay diagnosis, which may prove dangerous, since early detection of melanoma is critical; early melanomas are almost always curable, while those that advance beyond stage I become more difficult to treat. Amelanotic melanomas tend to recur or spread (metastasize) more often than melanomas with more typical features.<\/p>\n<p>While these melanomas lack pigment, they may have other melanoma warning signs to stay on the lookout for, such as asymmetry and an irregular border. In addition, more and more physicians today stress the importance of the \u201cE\u201d in the ABCDEs \u2013 evolution or change. The Skin Cancer Foundation recommends that you\u00a0<a href=\"https:\/\/www.skincancer.org\/early-detection\/self-exams\/\">examine your skin head to toe every month<\/a>, especially looking for any new mole\u00a0<em>or any sign of change in an existing mole<\/em>. If you spot anything new, changing or unusual, see a dermatologist without delay.<\/p>\n<p>To help you spot unusual melanomas, you can also use early recognition strategies\u00a0beyond the ABCDEs, such as the <a href=\"https:\/\/www.skincancer.org\/skin-cancer-information\/melanoma\/melanoma-warning-signs-and-images\/\">Ugly Duckling sign<\/a>.<\/p>\n<p>It also may help you to know that the ABCDEs apply mainly to the most common form of melanoma,\u00a0<em>superficial spreading melanoma<\/em>. There are actually\u00a0<a href=\"https:\/\/www.skincancer.org\/skin-cancer-information\/melanoma\/#four\">four major types of melanoma<\/a>, all of which look a little different than one another.<\/p>\n","protected":false,"gt_translate_keys":[{"key":"rendered","format":"html"}]},"excerpt":{"rendered":"<p>Amelanotic melanomas can resemble other skin cancers like basal cell or squamous cell carcinoma, or worse, may be mistaken for benign moles, scars or cysts. This can delay diagnosis, which may prove dangerous, since early detection of melanoma is critical; early melanomas are almost always curable, while those that advance beyond stage I become more difficult to treat.\u00a0<\/p>\n","protected":false,"gt_translate_keys":[{"key":"rendered","format":"html"}]},"author":1,"featured_media":3977,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[10],"tags":[3282,3284,8,9,3283],"class_list":["post-3961","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-skin-cancer-information","tag-abcde-melanoma","tag-amelanotic-melanoma","tag-detection","tag-melanoma","tag-skin-cancer-information"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v25.3 (Yoast SEO v25.3) - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Amelanotic Melanoma: It Doesn\u2019t Look Like Other 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